Fun with Lyme Science

“After ticks attach and begin feeding, the spirochetes rapidly multiply, down-regulate or *shed* OspA, and up-regulate OspC during their migration to the salivary glands (41).”

http://iai.asm.org/content/70/7/3382.full

So the OspA is there, in the sludge of the tick’s gut contents.

What happens to the OspA blebs?

Funny you should ask. Just a wild guess, but maybe they get excreted into the human victim every 5-20 minutes?

“In a blood-feeding tick, saliva production is the main mechanism of water excretion [3, 4]. Ticks alternate blood ingestion and salivation, each cycle lasting for 5–20 min at a time [5, 6]. The gut pumps water and electrolytes into the haemocoel, which go back to the host via saliva, while the meal is concentrated in the midgut.”

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2785505/

So, if a Lyme vaccine manufacturer claims that its product causes production of anti-OspA antibodies that supposedly get sucked up by a tick, travel to the tick’s gut and kill or otherwise disable the spirochetes, that’s a lie. Because what happens is the spirochetes slough off the OspA to produce OspC. They certainly don’t die. And the OspA blebs don’t just disappear. They make their way into the tick’s salivary glands up to 12 times per hour.

And guess what? It’s not just OspA that’s problematic. According to Mario Phillip of Tulane University, the other surface proteins are likely also triacyl, meaning that they DO the same thing as OspA.

Not only L-OspA but also Pam3Cys was able to induce IL-6 production. ****Since all spirochetal lipoproteins likely share the Pam3Cys modification**** it follows that any lipoprotein should be able to effect production of IL-6 from astrocytes.

So, it doesn’t really matter if you get injected with OspA, OspC, OspXYZ; if they’re all triacylated, that means you’re screwed. And what these triacyl lipoproteins DO is not pretty:

“IL-6 is produced by diverse immune and neural cells, including macrophages, B and T lymphocytes, which may enter the CNS from the periphery [43], as well as neurons, microglia and astrocytes [44]. In the CNS proper, IL-6 exerts both beneficial and destructive effects [45]. Destructive effects of IL-6 are associated with excess production of this cytokine. IL-6 overexpression is thought to be a factor in numerous CNS diseases, among which are AD, amyotrophic lateral sclerosis, MS, stroke and septic shock [45]. Since IL-6 is able to promote astrocyte proliferation [35], it is therefore thought to be a factor in astrogliosis. It is not clear whether astrogliosis is itself deleterious in diseases in which IL-6 overexpression is apparent, or a concomitant phenomenon.”

https://onlinelibrary.wiley.com/doi/pdf/10.1002/eji.200323872

What’s more, CDC and friends published that borreliosis is far more complicated than spirochetes expressing a single outer surface protein depending on environment. That means they know that it’s ridiculous to claim that a Lyme “vaccine” works AT ALL….let alone that it works via the tick’s ingestion of OspA-antibody-laden human blood.

“To our surprise, what we observed was not simply a matter of one protein being expressed in the gut and another in the host,” Dr. de Silva said. ”What the tick actually spits into the host is a bacteria population that is highly variable.”

“The study, whose co-authors were Dr. Jun Ohnishi, a postdoctoral researcher, and Dr. Joseph Piesman, of the division of vector-borne diseases at the Centers for Disease Control and Prevention in Atlanta, was reported last month in The Proceedings of the National Academy of Science.”

https://mobile.nytimes.com/2001/02/20/health/findings-boost-hope-for-better-lyme-vaccine.html

In US Patent 6,719,983 Alan Barbour agreed with Piesman and Ohnishi, describing what that highly variable bacteria population does:

“An important aspect of the invention is the recognition that Borrelia VMP-like sequences recombine at the vls site, with the result that antigenic variation is virtually limitless. Multiclonal populations therefore can exist in an infected patient so that immunological defenses are severely tested if not totally overwhelmed.”

What he’s saying is that the lipoproteins expressed by Borreliae are so widely variable that the immune system cannot fight the infection. “…immunological defenses are severely tested if not totally overwhelmed.”

And, just because I like this Report: Martin & Marques also published about the horrors of OspA on the brain while humoral immunity was blunted:

These results show that signaling through TLR1/2 in response to B. burgdorferi can elicit opposite immunoregulatory effects in blood and in brain immune cells, which could play a role in the different susceptibility of these compartments to infection.

https://www.ncbi.nlm.nih.gov/pubmed/16783164/

Here’s a review of the data on transmission time:

“A study by Piesman (CDC) et al found infected ticks with bacteria in their salivary glands and other organs at the onset of feeding, and even before feeding began.26 Lebet and Gern demonstrated that 11% of field-collected unfed nymphal ticks had systemic infection,42 and Leuba-Garcia et al found that 36% of unfed adult I. ricinus ticks collected in two districts of Switzerland had systemic infection, and they commented that this could impact transmission time in humans.43 These results suggest that in cases where the spirochetes are present in the tick salivary glands, they can be injected into the host during the preparatory transfers of antihistamines and anticoagulants prior to the commencement of feeding, ie, immediately after attachment of the tick to the host.”

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278789/

In other words, avoiding the bite is the only way to protect yourself from tick bite sepsis/post sepsis. CDC says spirochetes are already in the tick’s salivary glands when feeding begins, and that they express variable surface antigens when they’re there. A vaccine can’t work because these lipoproteins blunt the immune response; the immune system may be “totally overwhelmed,” according to OspA patent owner and former Willy Burgdorfer employee Alan Barbour. And the makers of OspA “vaccines” are frauds to claim that injecting OspA….

a) does not cause the disease;

b) can provide immunity against an organism that is designed to avoid the immune system through antigenic variation; and

c) turns human blood into tick disinfectant.

This has been a public service announcement brought to you by the people who know WTF is up with Lyme science. Wasn’t that fun?



Categories: Beaux's Favorites, Immunosuppression Diseases, Lyme 101, Lyme Disease

Tags: , , , , , , , , , , , , , , ,

2 replies

  1. A new “vaccine” is ready to be released and it seems useless I tell people over and over the truth of all this. So what is going to happen? Herds of people sick for a lifetime for known causes but who will be constantly and consistently lied to.

    Sorry I have been absent from posting.

    Liked by 1 person

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google+ photo

You are commenting using your Google+ account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this: